DJ Harvey, DJ Hell and Hunee will also play the Tuscan nightspot between now and the end of the month.
Diagonal Club has released the bulk of its April listings, running from the 4th through 26th.
The Tuscan venue, which opened in early 2012, has rapidly built a reputation as a go-to spot for quality house and techno in the area. The club will celebrate its second birthday this weekend, first inviting Dekmantel affiliatesKsoul & Muteoscillator to headline on Friday, before Beats In Space chief Tim Sweeney drops by for the part two on Saturday.
A week later, Hunee will top the bill at A New Music Experience, while scene veterans DJ Hell and DJ Harvey have been booked for sets on the 19th and 26th respectively. Harvey will appear in conjunction with the Red Bull Music Academy. Diagonal Club resides on Italy's north-west coast, a short car journey from the Tuscan city of Lucca.